In the recent debate over who would be best to answer 3:00am phone calls at the While House, most commentators have focused on the relative "experience" of Hilary Clinton, Barack Obama, and John MacCain. However, experience alone is the not the only measure of who is best to be hauled out of bed and faced with a crisis call. We should also consider basic elements of personality such as the degree of emotional response to stressful situations... Which candidate is most likely to answer the call with a level head and respond rationally, not emotionally?
Today, the NIH described research that finds a genetic factor in stress response variability. According to the press release:
Inherited variations in the amount of an innate anxiety-reducing molecule help explain why some people can withstand stress better than others...
Scientists led by David Goldman, M. D., chief of the NIAAA Laboratory of Neurogenetics, identified gene variants that affect the expression of a signaling molecule called neuropeptide Y (NPY)...
"NPY is induced by stress and its release reduces anxiety," said Dr. Goldman. ...
The researchers evaluated the NPY gene variants' effects on brain responses to stress and emotion. Using functional brain imaging, they found that individuals with the variant that yielded the lowest level of NPY reacted with heightened emotionality to images of threatening facial expressions. ...
In a preliminary finding, the low level NPY gene variant was found to be more common than other variants among a small sample of individuals with anxiety disorders. The researchers also found that low level NPY expression was linked to high levels of trait anxiety. "Trait anxiety is an indication of an individual's level of emotionality or worry under ordinary circumstances," explained Dr. Goldman.
So, will we one day be asking presidential candidates to submit genetic profiles so that we can objectively determine which is most likely to respond rationally and unemotionally to these 3:00am phone calls?
What sort of a world will we have once scientists are successful in working out the genetic code? Will genetic testing become a common criteria for a wide variety of jobs?
bob wyman
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